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Extend Healthspan

The products the evidence supports for extend healthspan, graded and tied to the protocols that call for them.

Nutricost

Strong ~$20

Nutricost Beta-Alanine Powder, an unflavored bulk powder at a low per-serving cost; brand-level testing, not per-lot certified.

Called for in Endurance & VO2 Max
Andy Galpin
Buy

LMNT Zero Sugar Electrolytes

Strong ~$25

Sodium, potassium and magnesium with zero sugar, the electrolyte-not-sports-drink profile the protocols call for, with a consistent…

Dan Go, Andy Galpin, Andrew Huberman
Buy

Thorne Magnesium Bisglycinate (powder)

Strong ~$32

For a general magnesium slot, glycinate is the best-evidenced form for sleep and relaxation; same NSF Certified for Sport pick as the…

Thomas DeLauer, Gabrielle Lyon, Casey Means
Buy

Nordic Naturals Ultimate Omega

Strong ~$32

High EPA and DHA per serving and the most independently batch-tested fish oil in the category (IFOS 5-star), which is fish-oil-specific…

Bryan Johnson, Sara Gottfried, Mark Hyman
Buy

Thorne Creatine (micronized monohydrate)

Strong ~$40

Creapure-grade micronized monohydrate, NSF Certified for Sport (the strictest lot-by-lot program), from the official supplement partner to…

Andrew Huberman, Bryan Johnson, Andy Galpin
Buy

Vital Proteins Collagen Peptides (unflavored)

Strong ~$45

Single-ingredient hydrolyzed peptides, unflavored so it stacks into any protocol, the most-reviewed collagen brand.

Gary Brecka, Mary Claire Haver, YourProtocol
Buy

Optimum Nutrition

Strong ~$55

Optimum Nutrition Gold Standard Isolate, tested for banned substances under the brand's own program; kept separate from the standard whey…

Gabrielle Lyon
Buy

Timeline

Strong ~$100

Timeline Mitopure, the best-evidenced urolithin A product of this group though notably more costly than the others; brand-level testing,…

Gabrielle Lyon
Buy

Adjustable dumbbells / resistance bands

Strong
Gabrielle Lyon

Handheld lactate meter

Strong
Called for in Zone 2 Endurance Base
Peter Attia

Indoor cardio machine

Strong
Called for in Zone 2 Endurance Base
Peter Attia

Kettlebell / dumbbells

Strong
Peter Attia

Rowing machine

Strong
Called for in Endurance & VO2 Max
Andy Galpin

Vitamin C serum + mineral sunscreen

Strong
Bryan Johnson

NOW

Moderate ~$16

NOW Vitamin C-1000 Sustained Release with Rose Hips, a long-standing brand pick; brand-level testing, not per-lot certified.

Gary Brecka
Buy

Jarrow Formulas Alpha Lipoic Sustain 300mg

Moderate ~$18

Correct sustained-release ALA form from a long-standing brand with facility-level cGMP and stated lab testing.

Tim Ferriss, Mark Hyman
Buy

NOW Foods Berberine HCl 500mg

Moderate ~$20

The straight berberine HCl form the evidence uses; NOW ran independent HPLC testing where 30 of 33 Amazon berberines failed potency and…

Mark Hyman, David Sinclair
Buy

Sports Research Vitamin D3 + K2 (MK-7)

Moderate ~$20

K2 is MK-7, the form the evidence supports; the more famous Thorne D and K2 uses MK-4 and fails that requirement.

Dom D'Agostino, Gabrielle Lyon, Louisa Nicola
Buy

Doctor's Best

Moderate ~$27

Doctor's Best High Absorption CoQ10 100mg, a widely used GMP-manufactured option; no third-party certification published.

Rhonda Patrick
Buy

Kasandrinos Organic Extra Virgin Olive Oil

Moderate ~$28

Single-estate, first cold-pressed current-harvest Greek EVOO, USDA Organic, with polyphenol content stated on the label. Polyphenol levels…

Mary Claire Haver, Mark Hyman, Bryan Johnson
Buy

Orgain

Moderate ~$28

Orgain Organic Plant Protein, a widely available organic plant-based blend; no third-party certification verified, GMP-manufactured.

Called for in The Blueprint Diet
Bryan Johnson
Buy

Thorne Basic Nutrients 2/Day

Moderate ~$30

A comprehensive daily multi in bioavailable forms, NSF Certified for Sport, same brand family as our creatine and magnesium picks.

Mark Hyman, Rhonda Patrick
Buy

Thorne Magnesium Bisglycinate (powder)

Moderate ~$32

Correct chelated bisglycinate form (not oxide), NSF Certified for Sport, and a powder so the dose titrates for sleep protocols.

Sara Gottfried, Mark Hyman, Sean O'Mara
Buy

Thorne Broccoli Seed Extract

Moderate ~$35

Broccoli seed extract standardized to sulforaphane glucosinolate (50mg SGS), the active compound, from a brand with a consistent testing…

Rhonda Patrick
Buy

Nordic Naturals

Moderate ~$40

Nordic Naturals Algae Omega, a vegan EPA/DHA source from a brand with per-lot third-party testing across its omega line; kept separate from…

Called for in The Omega-3 Protocol
Rhonda Patrick
Buy

Bowflex SelectTech 552

Moderate ~$365

The most-reviewed adjustable dumbbell, replacing 15 pairs of fixed weights in one unit.

Bret Contreras, Gabrielle Lyon, David Sinclair
Buy

Ice Barrel 400

Moderate ~$1190

Consistently the top-reviewed barrel-style plunge, with a brand-official Amazon storefront so it clears the counterfeit-risk bar.

Wim Hof, Andrew Huberman, David Sinclair
Buy

Barbell & plates set

Moderate
Gabrielle Lyon

Barbell / dumbbells

Moderate
Stacy Sims

Fish oil / algae oil

Moderate
Gary Brecka

Home sauna

Moderate
David Sinclair

Home sauna or sauna tent

Moderate
Rhonda Patrick

Multivitamin + creatine monohydrate

Moderate
Rhonda Patrick

Omega-3 + vitamin D3 & K2

Moderate
Thomas DeLauer, Mary Claire Haver

Protein

Moderate
Stacy Sims

Protein + creatine blend

Moderate
Mary Claire Haver

Soluble + insoluble fiber blend

Moderate
Mary Claire Haver

Third-party-tested fish oil

Moderate
Called for in The Omega-3 Protocol
Rhonda Patrick

Vitamin C serum + SPF

Moderate
Gary Brecka

NOW

Limited ~$10

NOW TMG (Trimethylglycine) 1000mg; evidence for some claimed uses is still emerging. Brand-level testing, not per-lot certified.

Gary Brecka
Buy

Organic India

Limited ~$14

Organic India Moringa, a widely available organic moringa leaf powder; no third-party certification verified, GMP-manufactured.

Rhonda Patrick
Buy

Double Wood

Limited ~$20

Double Wood Resveratrol 500mg, a straightforward single-ingredient dose; brand-level testing, not per-lot certified.

David Sinclair
Buy

Thorne B-Complex #6

Limited ~$22

Active methylated B forms (5-MTHF folate, methylcobalamin), not the cheaper cyano and folic-acid forms, NSF Certified for Sport.

Gary Brecka, Mark Hyman
Buy

Double Wood

Limited ~$23

Double Wood Fisetin 100mg; evidence here is early/preclinical, so treat this as an emerging pick rather than a settled one. Brand-level…

Bryan Johnson
Buy

Sports Research

Limited ~$26

Sports Research D3 5000IU, a widely reviewed pick in oil-based softgels for absorption; brand-level testing, not per-lot certified.

Rhonda Patrick
Buy

Codeage

Limited ~$34

Codeage Liposomal Glutathione 1000mg, a liposomal delivery form for better absorption; GMP-manufactured, no third-party certification…

Mark Hyman
Buy

Doctor's Best

Limited ~$34

Doctor's Best Kaneka Ubiquinol 100mg, the reduced (active) CoQ10 form using the reference Kaneka raw material; GMP-manufactured, no…

Mark Hyman
Buy

ProHealth

Limited ~$40

ProHealth Ca-AKG 1000mg; evidence here is early/preclinical, so treat this as an emerging pick. Brand-level testing, not per-lot certified.

Bryan Johnson
Buy

Thorne

Limited ~$43

Thorne Quercetin Phytosome, NSF Certified for Sport with per-lot testing and a phytosome delivery form for better absorption than plain…

Mark Hyman
Buy

Thorne

Limited ~$45

Thorne Curcumin Phytosome (Meriva), NSF Certified for Sport with per-lot testing and the Meriva phytosome form shown to improve absorption…

Mark Hyman
Buy

Double Wood

Limited ~$45

Double Wood Spermidine 10mg; evidence is still emerging, so treat this as an early-stage pick. Brand-level testing, not per-lot certified.

David Sinclair
Buy

Renue By Science NMN (liposomal, 500mg)

Limited ~$50

Of NMN brands with a genuine public per-batch COA, the most consistently cited as reputable. Caution: independent testing has found no detectable NMN in many marketplace listings, so verify the COA before buying.

Bryan Johnson, Mark Hyman, David Sinclair
Buy

Antioxidant blend

Limited
Called for in Blueprint Daily Protocol
Bryan Johnson

Cold plunge

Limited
Called for in Superhuman Protocol
Gary Brecka

Essential micronutrient capsules

Limited
Called for in Blueprint Daily Protocol
Bryan Johnson

Fisetin + quercetin

Limited
David Sinclair

Grounding mat

Limited
Called for in Superhuman Protocol
Gary Brecka

Longevity supplement blend

Limited
Called for in Blueprint Daily Protocol
Bryan Johnson

Methylated multivitamin

Limited
Called for in Superhuman Protocol
Gary Brecka

Mineral electrolytes / sea salt

Limited
Called for in Superhuman Protocol
Gary Brecka

Molecular hydrogen tablets

Limited
Called for in Superhuman Protocol
Gary Brecka

NAC / glycine

Limited
Gary Brecka

NMN or NR

Limited
Called for in Blueprint Daily Protocol
Bryan Johnson

Plant protein + extra-virgin olive oil

Limited
Called for in Blueprint Daily Protocol
Bryan Johnson

Third-party-tested moringa

Limited
Rhonda Patrick

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