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Hematologist-Oncologist, MCAS Clinician-Researcher · AIM Center for Personalized Medicine

Lawrence Afrin, MD

New protocols and grade changes land in My Protocols.

Hematologist-oncologist, MUSC-trained, former University of Minnesota Hematology-Oncology faculty. Sole author of the first book on mast cell activation syndrome (MCAS), published 2016, and one of the field's most-published clinician-researchers. MCAS itself remains a genuinely contested diagnosis outside the stricter, tryptase-based Consensus-2 criteria; that tension is named honestly here rather than presented as settled.

MCAS: The Step-Up Treatment Approach

Dr. Lawrence Afrin's step-up approach to MCAS: OTC H1/H2 antihistamines first, a thin-evidence supplement adjunct…

Lawrence Afrin, MDOngoing, physician-guided beyond step one

MCAS: The Low-Histamine Diet and Trigger Diary

The diet and tracking half of MCAS management: a symptom-food diary, a time-boxed low-histamine elimination trial,…

Lawrence Afrin, MD4-8 weeks initial trial, then ongoing

MCAS (Mast Cell Activation Syndrome)

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